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However, it was observed that large agglomerates of 117 nm TiO 2 caused higher pulmonary cytotoxicity in the mice inhalation study and more blood DNA damage in gavaged mice than small agglomerates (Murugadoss et al., 2020)

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When used alongside lifestyle modification and, where indicated, pharmacotherapy, these evidence-based supplements can meaningfully improve metabolic, hormonal, and reproductive outcomes for patients with PMOS