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If the ACO is eligible for the population adjustment as determined in paragraph (b)(3) of this section, the adjustment is equal to the product of the scaler calculated in paragraph (b)(2) of this section and the proportion of the ACO's assigned beneficiaries for the performance year who are enrolled in the Medicare Part D LIS or dually eligible for Medicare and Medicaid

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ccRCC cells enhance the glycolysis pathway to facilitate glucose uptake, lower the pH in tumor cells by lactic acid accumulation, and support a beneficial environment for their growth (Zh et al., 2023