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By inhibiting NNMT, it essentially takes the foot off that metabolic brake

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3 A more extensive list of drugs associated with acneiform eruptions includes halogenated aromatic hydrocarbons, antibiotics, nystatin, corticotropin, naproxen, hydroxychloroquine, oral contraceptives, halogenated chemicals, immunosuppressants, lithium, anticonvulsants, epidermal growth factor receptor inhibitors, tumor necrosis factor alpha antagonists, and vitamins B1 and B6 ( Table 1 )