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In the early 1980s, the concept obtained an additional key, the concomitant protection of the stomach endothelium[20,21] or Szabo’s vascular injury, as an early pathogenic factor in the development of ethanol-induced gastric hemorrhagic erosions

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This is because lots of supplements contain metals like zinc, copper, and chromium, which have been known to cause this unpleasant side effect, according to Cleveland Clinic