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In addition, proposed mechanisms include increased core temperature via effects on CB1 receptors in the thermoregulatory centers in the hypothalamus, skin vanilloid-1 receptor stimulation, and blood flow shift from viscera to skin.46 A second target is the TRPV1 receptor, also known as the capsaicin or vanilloid receptor.51 The TRPV1 receptors are distributed in various parts of the gastrointestinal tract and vagal afferents that innervate the stomach and intestine, and are also distributed in the enteric nervous system
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[DOI] [PubMed] [Google Scholar] 213.Kuźniak E., Kaźmierczak A., Wielanek M., Głowacki R., Kornas A