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Patients with prostate cancer and obesity have a greater likelihood of recurrence than patients who are not obese (Hu et al., 2014), and patients with colorectal cancer and obesity have an increased risk of all-cause mortality, cancer-specific mortality, recurrence, and shorter disease-free survival, compared to patients with colorectal cancer who are normal weight (Doleman et al., 2016)

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Mechanism studied Specifically, published studies examine Sermorelin’s binding to the GHRH receptor on pituitary somatotroph cells — a pathway associated with pulsatile GH release