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Therefore, attenuation of excessive ROS-induced cellular senescence, apoptosis, and extracellular matrix (ECM) synthesis, especially involving collagen, elastin, and glycosaminoglycans (GAGs), proves efficacious in the advancement of anti-aging therapeutics (Kammeyer and Luiten, 2015)

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For example, neurons co-cultured with astrocytes exhibit higher levels of glutathione compared to neurons cultured alone, demonstrating that astrocytes provide additional antioxidant defenses to neurons [104-106]