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However, the potential for increased bleeding risk due to additive antiplatelet effects from both curcumin and cilostazol, coupled with potential pharmacokinetic interactions (CYP inhibition) that could increase cilostazol exposure, requires careful clinical consideration

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As the most evolutionarily conserved UPR branch, the IRE1α-X-box binding protein 1 (XBP1) pathway determines cell fate under endoplasmic reticulum (ER) stress by regulating protein homeostasis and chaperone expression, but has never been functionally implicated in ferroptosis 10