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While its best-known role is in erythropoiesis (red blood cell formation), it’s also involved in: DNA synthesis Regeneration of bone marrow, GI lining, and respiratory tract lining Nervous system development and maintenance (11) Prevention of anemia Although a B12 deficiency isn’t as common as vitamin D or even folate, it still happens

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These findings should be overseen with glutamate as the major excitatory neurotransmitter in the central nervous system (i.e., cognitive functions such as learning and memory in the brain [200], the precursor of major inhibitory neurotransmitter GABA) but excitotoxic neuronal death as a direct result of high concentrations [201], and tight physiologic range that should be maintained [59]