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Unfortunately, the multitude of agents supposed to be involved did not resolve the conceptual problems that were initially shown with the prime agents, providing the limited therapeutic potential of prostaglandins in stomach lesions ( i.e

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The diagnostic criteria for hypertension were an average systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥90 mmHg (measured three times at 5-min intervals), or 24-h SBP ≥130 mmHg or 24-h DBP ≥80 mmHg, or a history of hypertension with treatment using antihypertensive medications (12)